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Mucoadhesion defined as attachment of synthetic or natural
materials to mucosal tissues has been widely exploited in
pharmaceutical forms. This multi-author book provides an up-to-date
account of current research on mucoadhesive materials and drug
delivery systems. The introductory section describes the structure
and physiology of various mucosal surfaces (oral, nasal, ocular,
gastrointestinal and vaginal mucosa). This is followed by chapters
on the various methods used to study mucoadhesion and to
characterise mucoadhesive properties of various dosage forms. The
final section will summarise information on traditional and novel
types of mucoadhesive materials, such as chitosan, thiomers, and
liposome-based formulations. This book is unique as there is
currently no modern book considering mucoadhesion - all other
existing books on the topic are either narrowly focused or more
than 10 years old. Furthermore, each contributor offers specialist
perspectives from a variety of global locations in both industrial
and academic research centres.
Noncovalent interactions play key roles in many natural processes
leading to the self-assembly of molecules with the formation of
supramolecular structures. One of the most important forces
responsible for self-assembly is hydrogen bonding, which also plays
an important role in the self-assembly of synthetic polymers in
aqueous solutions. Proton-accepting polymers can associate with
proton-donating polymers via hydrogen bonding in aqueous solutions
and form polymer-polymer or interpolymer complexes.There has been
an increased interest among researchers in hydrogen-bonded
interpolymer complexes since the first pioneering papers were
published in the early 1960s. Several hundred research papers have
been published on various aspects of complex formation reactions in
solutions and interfaces, properties of interpolymer complexes and
their potential applications. This book focuses on the latest
developments in the area of interpolymer complexation via hydrogen
bonding. It represents a collection of original and review articles
written by recognized experts from Germany, Greece, Kazakhstan,
Poland, Romania, Russia, UK, Ukraine, and the USA. It highlights
many important applications of interpolymer complexes, including
the stabilization of colloidal systems, pharmaceuticals, and
nanomaterials.
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